https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:14503 Wed 19 Apr 2023 13:38:51 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:13793 Wed 11 Apr 2018 17:12:08 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:37181 n = 18) or 2 g PS (PS, n = 18), 3 g OBG (OBG, n = 18), or combination of 2 g PS and 3 g OBG (PS-OBG, n = 18) per day for 6 weeks. Primary outcome was fasting plasma total cholesterol (TC) and secondary outcomes were LDL-cholesterol, LDL-C; HDL-cholesterol, HDL-C; triglycerides, TG and TC to HDL-cholesterol (TC:HDL) ratio. Results: TC and LDL-C were significantly lowered following PS (-4.6% and -7.6% respectively; p < 0.05), OBG (-5.7% and -8.6%; p < 0.01) and PS-OBG (-11.5% and -13.9%; p < 0.0001) administration. The reduction in TC in the PS-OBG group was significantly greater compared to PL (p < 0.001) and PS (p < 0.05). PS-OBG group had a significantly greater reduction in LDL-C compared to PL (p < 0.01) but not in comparison to PS or OBG groups. TC:HDL ratio was significantly reduced following PS-OBG (-8.9%; p < 0.01) only, and there was no significant difference found between groups. Plasma TG reduced by 8.4% following PS-OBG, however, this was statistically non-significant. Plasma HDL-C remained unchanged across all groups. Conclusions: Dietary supplementation with high-MW OBG and PS in a single functional food enhances their lipid-lowering potential. Blood cholesterol lowering by PS and OBG is additive. Delivery of these two bioactive nutrients in a single food allows optimisation of their lipid-lowering effects and may provide added heart health benefits with enhanced compliance. The trial was registered with the Australian New Zealand Clinical Trials Registry at http://www.anzctr.org.au/(ACTRN12618001455257).]]> Thu 27 Aug 2020 11:45:31 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30977 0.05) in CRP and serum ferritin across quartiles for either dietary pattern. In the fully adjusted model, the prevalence ratio (PR) of anaemia, comparing the fourth quartile to the first quartile, was 1.75 (95% CI: 1.33; 2.29) for a traditional dietary pattern, and 0.89 (95% CI: 0.68; 1.16) for a modern dietary pattern. The association between dietary patterns and anaemia is mediated by serum magnesium. Conclusion: Traditional dietary pattern is associated with a higher prevalence of anaemia among older Chinese. Future studies need to examine whether correcting micronutrient deficiency (e.g. magnesium) by promoting overall healthy diet, rather than iron supplementation, is a suitable strategy for anaemia prevention in older Chinese people.]]> Thu 21 Oct 2021 12:51:25 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36009 Thu 14 Apr 2022 11:03:10 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:1481 1 kg lost) or weight stable (≤1 kg lost) after an 8 week nutrition intervention period. Group survival duration (Kaplan Meier) and QoL (EORTC QLQ-C30) were compared. Predictors of weight stability were determined using logistic regression analysis. Results: Patients with weight stabilisation survived longer from baseline (log rank test 5.53, P=0.019). They also reported higher QoL scores (P=0.037) and a greater mean energy intake (P<0.001) at Week 8 than those who continued to lose weight. The absence of nausea and vomiting (OR 6.5, P=0.010) and female gender (OR 5.2, P=0.020) were independent determinants of weight stabilisation. Conclusions: Weight stabilisation over an 8 week period in weight-losing patients with unresectable pancreatic cancer was associated with improved survival duration and QoL.]]> Sat 24 Mar 2018 08:28:12 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:2259 Sat 24 Mar 2018 08:27:17 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17872 Sat 24 Mar 2018 07:56:12 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20302 Sat 24 Mar 2018 07:55:12 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:4850 Sat 24 Mar 2018 07:18:52 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38396 Mon 29 Jan 2024 17:47:06 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49574 Mon 22 May 2023 10:30:15 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:40753 Mon 18 Jul 2022 13:40:24 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42832 2 SD 3.9) participated in a crossover, randomized, controlled, double-blind clinical trial (registered under Australian New Zealand Clinical Trials Registry, identifier no. ACTRN12620000437965). Participants consumed a HFHE meal with a 250 mL dose of either intervention (anthocyanins-rich Queen Garnet Plum) or control (apricot) juice. Blood samples and blood pressure measures were collected at baseline, 2 h and 4 h following the HFHE meal. Vascular and microvascular function were evaluated at baseline and 2 h after the HFHE meal. Results: Participants had a higher 2 h postprandial flow-mediated dilatation (+1.14%) and a higher microvascular post-occlusive reactive hyperaemia (+0.10 perfusion units per mmHg) when allocated to the anthocyanin compared to the control arm (P = 0.019 and P = 0.049, respectively). C-reactive protein was lower 4 h postprandially in the anthocyanins (1.80 mg/L, IQR 0.90) vs control arm (2.30 mg/L, IQR 1.95) (P = 0.026), accompanied by a trend for lower concentrations of interleukin-6 (P = 0.075). No significant postprandial differences were observed between treatments for blood pressure, triacylglycerol, total cholesterol, serum derivatives of reactive oxidative metabolites, tumor necrosis factor alpha, interleukin-1 beta, or maximum microvascular perfusion following iontophoresis of acetylcholine. Conclusion: Fruit-based anthocyanins attenuated the potential postprandial detrimental effects of a HFHE challenge on parameters of vascular and microvascular function, and inflammatory biomarkers in overweight older adults. Anthocyanins may reduce cardiovascular risk associated with endothelial dysfunction and inflammatory responses to a typical high fat 'Western' meal. Further studies are required to better elucidate the clinical implications of postprandial biomarkers of CVD.]]> Mon 05 Sep 2022 12:31:21 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46360 Fri 18 Nov 2022 10:08:42 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51506 Fri 08 Sep 2023 11:57:56 AEST ]]>